November 1, 2008 Diagnostic Imaging. Vol. 30 No. 11 Smart probes and biomarkers spot earliest signs of cancer Gene profiles created for individual tumors could help tailor intensity of therapy to their aggressiveness, monitor the treatments’ effectiveness Molecular imaging is rapidly advancing as a biomedical modality that increases the understanding of underlying cellular mechanics and dynamics and adds a new dimension to the diagnosis and treatment of disease. It may be a sensitive and specific method for evaluating cancer by measuring the expression of genes that trigger oncogenesis and stratifying tumors on the basis of their biological characteristics. Central to any advancements is the development of biomarkers and targeted smart probes and the equipment to image them.
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