NSF’s underlying causes remain elusive

March 7, 2008 NSF’s underlying causes remain elusive H. A. Abella ------------------------------------------------------------------------------ The relationship between gadolinium-based contrast media for MRI and nephrogenic systemic fibrosis may be more nuanced than previously thought, according to several studies presented Friday at the 2008 ECR. Danish physicians rang the alarm in 2006 when they published data revealing a link between gadolinium-based contrast media and NSF in patients with acute renal failure. Within a year, European authorities had banned the use of gadodiamide and gadopentate dimeglumine in these patients. The FDA followed suit shortly after with a blanket alert for all five gadolinium agents marketed in the U.S.

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