Flat colorectal lesions show strong association with invasive carcinoma

March 6, 2008 Flat colorectal lesions show strong association with invasive carcinoma Shalmali Pal -------------------------------------------------------------------------------- Flat or depressed colorectal neoplasms are more likely than polyps to contain in situ or submucosal carcinoma, according to a study released Wednesday. Unfortunately, these nonpolypoid lesions may be missed by colon cancer screening methods, according to gastroenterologists based in Palo Alto, CA. "Nonpolyoid colorectal neoplasms are more difficult to detect by colonoscopy or CT colonography because the subtle findings can be difficult to distinguish from those of normal mucosa," wrote Dr. Roy Soetikno and colleagues in the Journal of the American Medical Association (2008;299:1027-1035).

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