Ultrasound spots mammo misses, but at high cost

July 1, 2008 Diagnostic Imaging. Ultrasound spots mammo misses, but at high cost False-positives, special training needs hamper routine use of screening US for high-risk women By Shalmali Pal -------------------------------------------------------------------------------- Screening ultrasound paired with mammography improved breast cancer detection in high-risk women, but the combination also caused a spike in the number of false positives, according to an update to the American College of Radiology Imaging Network 6666 trial. These results may render ultrasound less attractive than MRI in this patient population. "Supplemental screening ultrasound has the potential of depicting small, node-negative breast cancers not seen on mammography," wrote Dr. Wendie Berg, Ph.D., et al in the Journal of the American Medical Association (2008;299[18]:2151-2163).

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