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Thrombolysis Proves Effective Outside the 3-Hour Window

January 23, 2008 Diagnostic Imaging. Thrombolysis Proves Effective Outside the 3-Hour Window Delayed treatment outcomes compare with early CT thrombolysis if diffusion-perfusion mismatch is present Dee Rapposelli -------------------------------------------------------------------------------- MRI-assisted thrombolysis is as good as and perhaps better than CT-assisted thrombolysis, and it may be particularly valuable for patients treated outside of the prescribed 3-hour treatment window after stroke onset.1 These findings were part of a large multicenter European study reported at the 2007 International Stroke Conference in San Francisco in February by Peter D. Schellinger, MD, PhD, a professor of neurology at the University of Erlangen in Germany. The study, which compared standard CT-based thrombolysis (within the 3-hour treatment window) with MRI-based thrombolysis within and outside the 3-hour window, included 1210 patients from 5 stroke centers in Germany and Spain. CT-assisted thrombolysis within 3 hours of stroke onset was performed in 714 patients, MRI-assisted thrombolysis within 3 hours after stroke was performed in 322 patients, and MRI-assisted thrombolysis after 3 hours of stroke onset was performed in 174 patients. The mean onset to treatment time was 130, 136, and 279 minutes, respectively.

See full article and related articles at DiagnosticImaging.com
This article was republished with permission from CMPMedica, LLC

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