March 26, 2008 Report from SIR: Cryotherapy proves long-term effectiveness in primary renal cancer H. A. Abella -------------------------------------------------------------------------------- Results from two clinical trials demonstrate that cryoablation of renal cell carcinomas is effective at least a year after treatment in nearly all patients with lesions 4 cm or smaller. The studies suggest that cryotherapy could serve as an alternative to surgery. Interventionalist Dr. Christos Georgiades and colleagues at Johns Hopkins University Hospital assessed 35 patients with localized renal cell carcinoma confirmed by biopsy. All patients underwent CT-guided percutaneous cryoablation and quarterly follow-up for about four years. The investigators found the treatment showed 97% efficacy in tumors 4 cm or smaller and almost 90% efficacy in tumors up to 7 cm at one-year follow-up.
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