Report from ARRS: Study establishes infection as NSF risk factor

April 14, 2008 Report from ARRS: Study establishes infection as NSF risk factor H. A. Abella -------------------------------------------------------------------------------- New evidence has surfaced pinpointing specific potential causes of nephrogenic systemic fibrosis. Findings sustain its relationship to some gadolinium-based contrast media, but they also suggest that infection, certain patient demographics, and even some drugs could be strongly associated with the condition. The studies were released Monday at the 2008 American Roentgen Ray Society meeting in Washington, DC. Researchers from Duke University led by Dr. Lauren Golding reported strong evidence that patients with renal insufficiency who had sustained infections from surgery or inflammatory conditions previous to MR scanning are more likely than other high-risk patients to develop NSF. The association of NSF with infection was highly significant (p<0.001). It was established from retrospective reviewed data from eight patients who developed NSF at Duke between 2002 and 2006.

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