MRI of TIA faces barrier of therapeutic limitations

January 23, 2008 Diagnostic Imaging. MRI of TIA faces barrier of therapeutic limitations Screening tool may be ahead of its time, as results of recent trials fail to keep up with imaging advances Jordana Bieze Foster -------------------------------------------------------------------------------- A growing body of research indicates that MR diffusion-weighted imaging (DWI) can help predict risk of recurrent stroke in patients presenting with transient ischemic attack. But a lack of proven therapeutic options-underscored by recent setbacks in trials of neuroprotective agents-will limit opportunities for imaging to play a preventive role in this frustrating patient population. Recent evidence of MRI's predictive value in patients who have had a TIA came from researchers at the University of Pennsylvania, who found that patients with acute (within 48 hours) infarction on DWI were significantly more likely than patients with negative DWI findings to experience stroke, death, or other high-risk outcome within 90 days.1

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