Molecular imaging scientist shares Nobel Prize for Chemistry

December 1, 2008 Diagnostic Imaging. Vol. 30 No. 12 Molecular imaging scientist shares Nobel Prize for Chemistry Roger Tsien, Ph.D., addressed the media Oct. 8 after learning he would share the 2008 Nobel Prize for Chemistry with Osamu Shimomura, Ph.D., and Martin Chalfie, Ph.D., for the discovery and application of green fluorescent protein as a tagging tool in bioscience and molecular imaging. Shimomura isolated the protein from a jellyfish in 1961 as a researcher at Princeton University. Chalfie demonstrated at Columbia University that the fluorescing protein could tag intracellular material in a roundworm. At the University of California, San Diego, Tsien engineered a series of mutations creating a palette of fluorescing molecular dyes (right) that have revolutionized small animal optical imaging and molecular pharmaceutical research. (Provided by UCSD)

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