Liver MR protocols address fibrosis threat

September 30, 2008 Diagnostic Imaging. Liver MR protocols address fibrosis threat Careful screening and a variety of contrast agents offer clinicians safe options for at-risk patients -------------------------------------------------------------------------------- The apparent link between nephrogenic systemic fibrosis and certain gadolinium-containing MR contrast media has led to a tightening of procedures in radiology departments worldwide. Steps have been implemented to identify those patients who are most at risk of developing the debilitating condition, which leads to sclerodema-like skin thickening and discoloration and fibrosis of vital internal organs. A proportion of patients who contract NSF will die from the condition. Radiologists dealing with referrals from urology and hepatology departments have undoubtedly been affected the most. To date, NSF has been observed only in patients with impaired kidney function. This category may include patients with advanced chronic liver disease or those who have acute liver failure.

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