Intensity-modulated breast therapy approach reduces radiation-induced dermatitis

April 29, 2008 Intensity-modulated breast therapy approach reduces radiation-induced dermatitis Shalmali Pal -------------------------------------------------------------------------------- Preventing adverse skin reactions during breast radiotherapy is a challenge. Attempts to address the problem with topical creams or hygiene have been unsuccessful. Instead, Canadian researchers have gone back to the source of the problem and found that using intensity-modulated radiation therapy can reduce acute dermatitis, especially when compared with traditional whole-breast radiotherapy. Dr. Jean-Philippe Pignol and colleagues conducted a multicenter phase III double-blinded clinical trial comparing IMRT with standard radiation therapy with wedge compensation in 331 women with early-stage breast cancer. Researchers came from the Sunnybrook Health Sciences Centre in Toronto, Vancouver Island Cancer Centre in Victoria, Durham Regional Cancer Centre in Osahwa, and Hôpital Notre-Dame in Montreal. They published their findings in the Journal of Clinical Oncology.

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