Hormone therapy reduces mammography’s effectiveness

March 28, 2008 Hormone therapy reduces mammography’s effectiveness Don Rauf -------------------------------------------------------------------------------- Treating the hot flashes, mood swings, and other symptoms of menopause with hormone therapy combining estrogen and progesterone compromises the diagnostic performance of mammography, according to a report from the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center. Women receiving both hormones had a higher chance of abnormal mammograms and breast biopsies. Oncologist Dr. Rowan Chlebowski and colleagues reviewed the cases of 16,608 postmenopausal women, 8506 of whom received a combination of estrogen and progesterone and 8102 who were given a placebo. All had participated in the Women's Health Initiative clinical trial from 1993 to 1998. They had received a mammogram and breast examination annually, with biopsies performed according to a physician's judgment.

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