Contrast-induced nephropathy fears ease

July 24, 2008 Contrast-induced nephropathy fears ease H. A. Abella -------------------------------------------------------------------------------- Ten years of clinical data from more than 30,000 patients suggest the estimated risk of sustaining renal damage from iodinated contrast media may have been blown out of proportion, according to Columbia University researchers. With proper scientific validation, contrast may be used even in patients with renal failure. Iodinated contrast agents used on CT exams have been blamed for kidney dysfunction for decades, as the clinical literature propagated the concept of contrast-induced nephropathy. Most studies on the subject, however, lacked the means to distinguish contrast-induced nephropathy from other causes of the condition, said principal investigator Dr. Jeffrey Newhouse, director of the division of abdominal imaging at Columbia-Presbyterian Medical Center in New York City.

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