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Patients who have suffered with fluctuating stroke symptoms have great chances of benefitting from treatment with tissue plasminogen activator (tPA).

Research has indicated that patients who have suffered with fluctuating stroke symptoms have great chances of benefitting from treatment with tissue plasminogen activator (tPA).
A report says that individuals who have suffered from fluctuating stroke symptoms can benefit from tissue plasminogen activator (tPA) treatment. This study was published in the “Archives of Neurology”.

Ozcan Ozdemir and his colleagues looked at around one hundred and twenty seven stroke patients who were then treated with wither intravenous or intra-arterial tissue plasminogen activator (tPA). Out of those, 13 patients had a median of around 4 symptom fluctuations during their life time. Report also indicates that Individuals with fluctuating symptoms had milder strokes at baseline when compared to those with stable symptoms, but nonetheless the patients did not differ in risk factors, stroke etiology, or time to thrombolysis.

They also found that patients who had fluctuating symptoms did have radiologic evidences of cerebral infarctions, and yet had all the favourable outcomes after thrombolysis. Meanwhile, out of all the patients with stable systems only 59.6 percent achieved good outcomes. The findings also ends to suggest that delaying or withholding thrombolytic therapy in patients with fluctuating symptoms is not warranted.

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