Ulcerated Gastric Lymphoma

This patient had a large ulcerated tumour on the lesser curvature of the stomach. Gastrectomy specimen showed gastric lymphoma. The differential diagnosis is gastric carcinoma and gastrointestinal stromal tumour (GIST). The stomach is the commonest site of extranodal lymphoma (25%), but gastric lymphoma represents only 5% of all gastric malignancies. Most are B cell non-Hodgkins lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) and are associated with Helicobacter pylori.
Reference:
1. Dahnert W. Radiology Review Manual, 5th edition. Lippincott, Williams and Wilkins 2003
2. Kumar V. et al Robbins and Cotran Pathologic Basis of Disease, 7th edition, Elsevier Saunders 2005
Credit: Dr Donna D'Souza
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