Phthisis Bulbi

Phthisis bulbi, also known as end-stage eye, is an atrophic scarred and disorganised globe that may result from a variety of severe ocular insults. Dystrophic calcification is common. Causes of this end-stage damage include trauma, infection, other inflammatory processes, radiation, chronic retinal detachment, persistent hyperplastic primary vitreous and retinoblastoma. The globe is non-functioning thus the patient is blind in that eye. Enucleation +/- prosthesis insertion is performed if there is associated chronic pain or for cosmetic reasons.
References:
1. Digital Journal of Opthalmology
2. Digital Reference of Opthalmology
Credit: Dr Donna D'Souza
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