Teaching File - Chondrocalcinosis CPPD Knee

Calcium pyrophosphate dihydrate disease (CPPD) is a rheumatologic disorder with varied clinical manifestations due to precipitation of calcium pyrophosphate dihydrate crystals in the connective tissues. It is more commonly known by alternative names that specify certain clinical or radiographic findings, although neither is synonymous with CPPD. Pseudogout refers to the clinically evident acute synovitis with red, tender, and swollen joints that may resemble gouty arthritis. This image serves as an excellent demonstration of chondrocalcinosis that can be seen in CPPD at the knee joint.