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Complications of hepatic arterial infusion chemotherapy.
Pozniak MA, Babel SG, Trump DL.
Department of Radiology, University of Wisconsin Hospital and Clinics, Madison 53792.
Radiographics. 1991 Jan;11(1):67-79
Chemotherapy by direct hepatic arterial infusion (HAI) results in reduction in tumor mass in a large percentage of patients. The authors reviewed records for 45 patients with metastatic cancer of the gastrointestinal tract who underwent HAI chemotherapy with floxuridine, administrated via an implanted pump. Twenty-seven of the 45 patients suffered complications, including gastrointestinal ulceration (18%), hepatitis (24%), sclerosing cholangitis (7%), and abscess (2%). The complication rates in this series were similar to those previously reported. The toxicity of HAI chemotherapy continues to limit its efficacy.
Posted via PubMed for educational and discussion purposes only.
Link to PubMed Reference
Department of Radiology, University of Wisconsin Hospital and Clinics, Madison 53792.
Radiographics. 1991 Jan;11(1):67-79
Chemotherapy by direct hepatic arterial infusion (HAI) results in reduction in tumor mass in a large percentage of patients. The authors reviewed records for 45 patients with metastatic cancer of the gastrointestinal tract who underwent HAI chemotherapy with floxuridine, administrated via an implanted pump. Twenty-seven of the 45 patients suffered complications, including gastrointestinal ulceration (18%), hepatitis (24%), sclerosing cholangitis (7%), and abscess (2%). The complication rates in this series were similar to those previously reported. The toxicity of HAI chemotherapy continues to limit its efficacy.
Posted via PubMed for educational and discussion purposes only.
Link to PubMed Reference
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